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New MACI Procedure Restores Cartilage, Preserves Joints

Smiling doctor in a white coat, light blue shirt, and dark tie against a neutral background.

Peter Yeh, MD, is specialty trained in MACI, an innovative technique that restores cartilage and preserves joints by using a patient’s own cells to repair knee cartilage damage. Offers a viable solution for younger adults and athletes who want to continue their active lifestyle.

Mandy Chaput is constantly on the move keeping up with her two active young boys and her career as Director of Early Learning and School Age Programs.

A few years ago, Mandy began experiencing pain in her left knee although she has never had an injury and is in her 30s, much younger than when age-related joint problems arise. It wasn’t long before she could no longer keep up with her active lifestyle. The pain became constant, keeping her up at night and causing popping and cracking during the day.

When Mandy sought medical attention, an MRI revealed that some of the cartilage in her knee was torn down to bone. Doctors told her that surgery would only make the condition worse and her only option was physical therapy.

“The thought of limiting my activity was not easy for me to grasp,” said Mandy. “I was not ready to throw in the towel on my knee.”

Luckily, Mandy found Dr. Peter Yeh, an orthopedic surgeon at Agility Orthopedics who is one of just a handful of surgeons in the region trained to perform a new cartilage regeneration procedure. Known as membrane-induced autologous chondrocyte implantation, or MACI, the innovative technique restores cartilage and preserves joints by using a patient’s own cells to repair knee cartilage damage instead of a cleanup or debridement procedure, a marrow stimulation procedure, a donated cartilage-bone transplant or even the traditional metal or plastic devices used in knee-replacement surgery.

Dr. Yeh recommended MACI to Mandy.  “Traditionally, there hasn’t been a good fix to restore torn cartilage. It is normally removed if it continues to bother the patient.  However, the absence of the cartilage essentially creates a defect that can continue to cause pain, soreness and swelling,” explained Dr. Yeh. “Cartilage restoration with MACI can preserve a joint and delay joint replacement for many patients. This surgical technique offers a viable solution for younger adults and athletes who want to continue their active lifestyle.”

The MACI procedure is comprised of two steps. First, the surgeon takes a sample of cells from the torn cartilage. This sample is sent off to a lab where, over the course of four to six weeks, the patient’s cartilage cells are replicated and placed onto a membrane. The second part of the procedure involves attaching the cartilage cells back into the knee, where it will mature over the successive 10-12 months. Mandy had the procedure done at Melrose Wakefield Hospital, one of the two hospitals where Dr. Yeh is affiliated.

“There are many benefits to the MACI procedure,” said Dr. Yeh. “Rebuilding the cartilage will keep the cushion between the bones intact, which could reduce the risk of developing arthritis in the future. Also, by using and regenerating your own cells, you eliminate the possibility of your body rejecting the new cartilage.”

Mandy recently completed the second part of the MACI procedure and has begun the rehabilitation process for her knee.  “I’m looking forward to resuming my life and being pain free,” said Mandy.

Learn more about Dr. Yeh.
For an appointment and information on the MACI procedure, call 781-279-7040
or request an appointment online. 

What Our Patients Have to Say

I can not stop raving about how good this place is for healing and getting your mobility back after an injury. You will make a good decision to attend this place of business and you will be in good, qualified hands to regain your strength back. Everyone is extremely nice and professional. I would recommend it to anyone who is in need of physical therapy. They do a terrific job and leave you feeling as though you can overcome any obstacle.

Kristen B.

If you’re an athlete this is the place to go. These people really know what they’re doing. I went here for a torn MCL a month ago. They x-rayed my knee as soon as I got there. Dr. Zahner is as professional as they come, very straight forward and helpful. Would’ve been a very long road to recovery had I not found this place.

Austin S.

Agility Orthopedics are great! I followed Dr. Zahner to Agility from where he was before at North Suburban Orthopedics! Everyone at Agility is very professional and very nice and are willing to answer any questions you may have! This was not the case at the other place! I would recommend Agility to anyone!

Judy W.

I was treated by Chase Conway for an issue with my elbow, and I can confidently say he was extremely professional throughout the entire process. He was direct and focused on exactly what I needed, always demonstrating precision and a clear understanding of what he was doing. He took great care of my elbow, which was a major concern for me, and his expertise made all the difference.

Kesia L.

First visit. Dr. Sherman was kind, compassionate, an active listener to my concern/issue, and had excellent patient/provider relations. He discussed the treatment plan and walked me through the whole procedure. Above and beyond his knowledge, his exemplary bedside manner should be an example to others.

Rob Q.

As always, I enjoyed my visit with Dr Kapassi. He took the time I needed, to listen to my issues, from the last visit I made last year. After asking several questions related to my health, he gave me a few options regarding treatment. I told him I'd like to consider those options. He agreed. At no time did he rush me or made me feel as if I wasting his precious time.

Janice H.

Very pleased with the prompt scheduling and medical guidance from Dr. Zahner, I've been having left hip issues for some time now, 3 months ago I visited a different Dr and was not happy so I went to Dr Zahner for 2nd advice. He was very thorough and offered several helpful scenarios, (not a potential hip replacement) 5 Stars and 2 thumbs up from this 63 year old triathlete!

Bob B.

I have been going to Agility Orthopedics for years now. As a Disabled Veteran, I refused to be seen at the VA. These are the people I trust to complete their due diligence when helping patients, taking our concerns to heart and ensuring patients safety/health are priority 1!! Highly Recommend!!

David B.

Dr. Anderson was able to see the actual problem I had within minutes that other doctors I had seen were unable. He's super friendly and the physical treatments he had me doing has helped me enormously. I can't say enough nice things about the man.

Brian R.